Iloprost CAS NO.78919-13-8

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 This chemical is called Iloprost [INN:BAN], and its systematic name is Pentanoic acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)-. With the product categories of Antianginal Drugs; Cardiovascular Drugs, its classification codes are Cardiovascular Agents; Drug / Therapeutic Agent; Hematologic Agents; Platelet Reproductive Effect; Treatment of pulmonary hypertension [prostacyclin analogue]; Vasodilator agents. The CAS registry number of this chemical is 78919-13-8. Additionally, it should be stored at -20°C. 

Other characteristics of the Iloprost [INN:BAN] can be summarised as followings: (1)XLogP3-AA: 2.8; (2)H-Bond Donor: 3; (3)H-Bond Acceptor: 4; (4)Rotatable Bond Count: 8; (5)Exact Mass: 360.23006; (6)MonoIsotopic Mass: 360.23006; (7)Topological Polar Surface Area: 77.8; (8)Heavy Atom Count: 26; (9)Formal Charge: 0; (10)Complexity: 606; (11)Isotope Atom Count: 0; (12)Defined Atom StereoCenter Count: 4; (13)Undefined Atom StereoCenter Count: 2; (14)Defined Bond StereoCenter Count: 2; (15)Undefined Bond StereoCenter Count: 0; (16)Covalently-Bonded Unit Count: 1; (17)Feature 3D Acceptor Count: 4; (18)Feature 3D Donor Count: 2; (19)Feature 3D Anion Count: 1; (20)Feature 3D Hydrophobe Count: 3; (21)Feature 3D Ring Count: 2; (22)Effective Rotor Count: 9; (23)Conformer Sampling RMSD: 1.2; (24)CID Conformer Count: 275.

Synthesis of this chemcial: The Iloprost [INN:BAN] could be obtained by compound I.

Uses of this chemical: This chemical is an eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. Its actions are similar to prostacyclin. The Iloprost [INN:BAN] produces vasodilation and inhibits platelet aggregation. It's used for angina, atherosclerosis.